Glucocorticoid medications given in primary care settings are associated with suicidal behaviors and severe neuropsychiatric disorders, new research suggests.
In a large, population-based study of adult patients in the United Kingdom (UK), those receiving glucocorticoids were almost 7 times more likely to commit or attempt suicide, more than 5 times more likely to develop delirium, more than 4 times more likely to develop mania, and almost twice as likely to develop depression than those with the same underlying conditions who did not receive the medications.
In addition, patients younger than 30 years were at particular risk for suicide attempts, women were more at risk for depression, and men were at especially increased risk for mania and delirium/confusion/disorientation. Higher dosages of the medications were also linked to an overall greater risk for adverse outcomes.
"Steroid-treated patients do not always know that the neuropsychiatric symptoms that they are experiencing are induced by the treatment. They may, for instance, think that they are induced by the underlying disease," lead author Laurence Fardet, MD, PhD, from the Department of Internal Medicine at Saint-Antoine Hospital in Paris, France, told Medscape Medical News.
"Therefore, I believe that physicians must be aware that these neuropsychiatric adverse events are frequent and potentially life-threatening in order to better inform the patient and their family, and to avoid steroids when possible," said Dr. Fardet.
With data for almost 3500 glucocorticoid-treated patients included, the investigators note that this is the largest trial to date to examine these adverse outcomes.
http://psychiatryonline.org/article.asp ... eID=519047
又一個藥中鏢....這次是steroid...
版主: 版主021
Re: 又一個藥中鏢....這次是steroid...
Method:
Data were obtained for all adult patients registered between 1990 and 2008 at U.K. general practices contributing to The Health Improvement Network (THIN) primary care database. The incidence rates for the outcomes of interest were assessed in patients who received prescriptions for oral glucocorticoids and compared with those in patients who did not receive such prescriptions. The predictors of these outcomes in exposed patients were ascertained using Cox proportional hazards models.
杜老: 所以...不知道吸入劑型有沒有影響 ?
Data were obtained for all adult patients registered between 1990 and 2008 at U.K. general practices contributing to The Health Improvement Network (THIN) primary care database. The incidence rates for the outcomes of interest were assessed in patients who received prescriptions for oral glucocorticoids and compared with those in patients who did not receive such prescriptions. The predictors of these outcomes in exposed patients were ascertained using Cox proportional hazards models.
杜老: 所以...不知道吸入劑型有沒有影響 ?
傳說中的杜老爺是也 ! http://mypaper.pchome.com.tw/bear1002
-
- 榮譽院長級
- 文章: 59129
- 註冊時間: 週四 3月 26, 2009 8:10 pm
- 來自: 集合住宅
-
- 註冊會員
- 文章: 747
- 註冊時間: 週六 7月 25, 2009 10:15 pm
Re: 又一個藥中鏢....這次是steroid...
下次的研究可能是
憂鬱症用藥可能會使人自殺率多很多倍(以有吃憂鬱症用藥與沒吃憂鬱症用藥來比較)
viagra可能會使人impotent (以有吃的人與沒吃的一般人來比)
(爽) garbage in , garbage out
憂鬱症用藥可能會使人自殺率多很多倍(以有吃憂鬱症用藥與沒吃憂鬱症用藥來比較)
viagra可能會使人impotent (以有吃的人與沒吃的一般人來比)
(爽) garbage in , garbage out
盡心盡力,沒人在意 掏心掏肺,當場作廢 江河日下,人心不古 依法看診,安全下庄
王維‧<酌酒與裴迪>
酌酒與君君自寬,人情翻覆似波瀾。白首相知猶按劍,朱門先達笑彈冠。
草色全經細雨濕,花枝欲動春風寒。世事浮雲何足問,不如高臥且加餐。
王維‧<酌酒與裴迪>
酌酒與君君自寬,人情翻覆似波瀾。白首相知猶按劍,朱門先達笑彈冠。
草色全經細雨濕,花枝欲動春風寒。世事浮雲何足問,不如高臥且加餐。
-
- V1
- 文章: 1758
- 註冊時間: 週一 9月 18, 2006 7:17 pm
Re: 又一個藥中鏢....這次是steroid...
這要醫師或研究人員才懂,一般民眾哪懂,只會引發恐慌,最後結論就是所有西藥都不能吃g96510083 寫:下次的研究可能是
憂鬱症用藥可能會使人自殺率多很多倍(以有吃憂鬱症用藥與沒吃憂鬱症用藥來比較)
viagra可能會使人impotent (以有吃的人與沒吃的一般人來比)
(爽) garbage in , garbage out
-
- 公會及協會
- 文章: 10178
- 註冊時間: 週四 10月 26, 2006 11:49 pm
- 來自: 台北市
Re: 又一個藥中鏢....這次是steroid...
那乾脆等死好了,不用就醫了WW 寫:這要醫師或研究人員才懂,一般民眾哪懂,只會引發恐慌,最後結論就是所有西藥都不能吃g96510083 寫:下次的研究可能是
憂鬱症用藥可能會使人自殺率多很多倍(以有吃憂鬱症用藥與沒吃憂鬱症用藥來比較)
viagra可能會使人impotent (以有吃的人與沒吃的一般人來比)
(爽) garbage in , garbage out
在目前高風險的時代,只願能:[北風北安全下庄]